Health effects of berries
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* In vitro/Nonclinical studies on berries and their components:
KähkönenM. et al. 1999. Antioxidant activity of plant extracts containig phenolic compounds. J. Agric. Food Chem. 47: 3954-3962.
Puupponen-Pimiä R. et al.2001. Antimicrobial properties of phenolic compounds from berries. J. Appl. Microbiol. 90: 494-507.
Kähkönen M. et al. 2003. Berry anthocyanins: isolation and antioxidant activities. J. Agric. Food Chem. 83:1403-1411.
Nohynek L. J. et al. 2006. Berry phenolics: antimicrobial properties and mechanisms of action against severe human pathogens. Nutr. Cancer 54: 18-32.
Misikangas M. et al 2007. Three nordic berries inhibit intestinal tumorigenesis in multiple intestinal neoplasia/+ mice by modulating beta-catenin signaling in the tumor and transcription in the mucosa. J. Nutr. 137: 2285-2290.
Kähkönen M. et al. 2012. Antioxidant activity of isolated ellagitannins from red raspberries and cloudberries. J. Agric. Food. Chem. 60: 1167-1674
Stoner G. D. and Seeram N. P. 2011. Berries and Cancer Prevention. A book, 303 p. Springer, New York.
Zhang H.-M. 2014. Research progress on the anticarsinogenic actions and mechanisms of ellagic acid. Cancer Biol. Med. 11:92-100.
Jiang F. et al. 2017. Flavonoids from sea buckthorn inhibit the lipopolysaccharide induced inflammatory response in RAW264.7 macrophages through the MAPK and NF-kB pathways. Food Funct. 22:1313-1322.
Päivärinta E. et al. 2017. Changes in intestinal, gut microbiota, and expression of energy metabolism-related genes explain adenoma growth in bilberry and cloudberry-fed ApcMin Mice. Nutr. Res. 36: 1285-1297.
Päivärinta E. 2017. Cloudberry (Rubus chamaemorus) and its components as chemopreventive constitents in ApcMin mice and human colon adenocarcinoma cells. Academic Dissertation, 82 p. Dissertationes Schola Doctoralis Scientiae Circumiectalis, Alimentariae, Biologicae.
** Clinical studies on berries:
Marniemi et al. 2000. Partial resistance of low density lipoprotein to oxidation in vivo after increased intake of berries.Nutr. Metab. Cardiovasc. Dis. 10, 331-337.
Erlund I. et.al. 2008. Favourable effects of berry consumption on platelet function, blood pressure and HDL chlolesterol. Am. J. Clin. Nutr. 87, 323-331.
Lehtonen H.-M. et al. 2010. Berry meals and risk factors associated with metabolic syndrome. Eur. J. Clin Nutr. 64, 614-621.
Krikorian R. et al. 2010. Blueberry supplementation improves memory in older adults. J.Agric. Food Chem. 58: 3996-4000.
Linnamaa P. et.al. 2010. Blackcurrant seed oil for prevention of atopic dermatitis in newborns: a randomized, double-blind, placebo-controlled trial. Clin Exp. Allergy. 40, 1247-1255.
Kolehmainen M et.al. 2012. Bilberries reduce low-grade inflammation in individuals with features of metabolic syndrome. Mol.Nutr. Food Res. DOI 10.1002/mnfr.201200195.
Kamiya K. et.al. 2013. Effect of fermented billberry extracts on visual outcomes in eyes with myopia: a prospective, randomized, placebo-controlled study. J.Ocul.Pharmacol. Ther. 29, 356-359.
Törrönen R. et.al.2013. Postprandial glycaemic response to berry nectars containing inverted sucrose. J.Nutr.Sci. 6, 1-7.
Törrönen R. et.al. 2017. Berries Reduce Postbrandial Insulin Responses to Wheat and Rye Breads in Healthy Women. J.Nutr.Sci. 143, 430-436.
Overall J. et.al. 2017. Metabolic Effects of Berries with Structurally Diverse Anthocyanins. Int. J. Mol. Sci. 18, 422. DOI: 10.3390/ljms 18020422.
Ledda A. et.al. 2017. Highly standardized cranberry extract supplementation (Anthocran®) as prophylaxis in young healthy subjects with recurrent urinary tract infections. Eur. Rev. Med. Pharmacol. Sci. 21, 389-393.
*** Content of polyphenols in berries:
Häkkinen S. et al. 1999. Content of the Flavonols Quercetin, Myricetin, and Kaempferol in 25 edible Berries. J. Agric. Food Chem. 47, 2274-2279.
Häkkinen S. 2000. Flavonols and Phenolic Acids in Berries and Berry Products. Doctoral Thesis. Kuopio University Publications. D, Medical Sciences, no 221.
Määttä-Riihinen K. R. et al.2004 Distribution and contents of phenolic compounds in eighteen Scandinavian berry species. J. Agric. Food Chem. 52: 4477-4486
Mattila P. et.al. 2006. Phenolic acids in berries, fruits and beverages. J.Agric. Food Chem. 52, 4477-4486.
Koponen J. et.al. 2007. Contents of Anthocyanins and ellagitannins in foods consumed in Finland. J. Agric. Food Chem. 55, 1612-1619.
Ovaskainen M.-L. et al. 2008. Dietary intake and major food sources of polyphenols in Finnish adults. J.Nutr. 138, 562-566.
Hellström J. et.al. 2009. Proanthocyanidins in common food products of plant origin. J.Agric. Food Chem. 57, 7899-7906.